Description

2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ol is a high-purity pyrrolopyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study enzyme function and cellular signaling.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ol
CAS No.	1201784-89-5
Molecular Formula	C7H7N3OS
Molecular Weight	181.21 g/mol
Synonyms	4-Hydroxy-2-(methylthio)-7H-pyrrolo[2,3-d]pyrimidine; 2-Methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol; 2-(Methylthio)-4-hydroxy-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidin-4-ol, 2-(methylthio)-; CAS 1201784-89-5
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.