Description

1-Chloroethyl 2,4-Dichloro-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within medicinal chemistry research and development. It is primarily sought by pharmaceutical manufacturers and R&D organizations engaged in developing targeted therapies, where precise chemical architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• API Synthesis: Serves as a key building block in the production of Active Pharmaceutical Ingredients (APIs) for potential use in oncology, antiviral, or other therapeutic areas.
• Process Development & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to pilot and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	1-Chloroethyl 2,4-Dichloro-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate
CAS No.	1201781-22-7
Molecular Formula	C12H10Cl3N3O2
Molecular Weight	334.58 g/mol
Synonyms	1-Chloroethyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-6-carboxylate; 2,4-Dichloro-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylic acid 1-chloroethyl ester; 6(5H)-Carboxylic acid, 7,8-dihydro-2,4-dichloropyrido[4,3-d]pyrimidine-, 1-chloroethyl ester; (1-Chloroethoxy)carbonyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; CAS 1201781-22-7
EINECS	Contact for details

Quality Control

Our 1-Chloroethyl 2,4-Dichloro-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.