Description

2,6-Difluoro-4-Methylbenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive aldehyde group, enabling precise molecular modifications to enhance the properties of target compounds. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides, where fluorine incorporation improves metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, enhancing the performance and stability of display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Organic Ligand Preparation: Utilized in the synthesis of fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,6-Difluoro-4-Methylbenzaldehyde
CAS No.	1201597-22-9
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	4-Methyl-2,6-difluorobenzaldehyde; 2,6-Difluoro-p-tolualdehyde; 2,6-Difluoro-4-methylbenzenecarboxaldehyde; 2,6-Difluoro-4-tolualdehyde; 4-(Difluoromethyl)-3-fluorotoluene (tautomer); Benzaldehyde, 2,6-difluoro-4-methyl-; 1201597-22-9 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-4-Methylbenzaldehyde is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.