Description

4-Bromo-2-Fluoro-6-Iodoaniline is a halogenated aniline derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its unique combination of bromo, fluoro, and iodo substituents on the aniline core makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry for creating fluorinated and halogenated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the halogen atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) due to the presence of reactive bromo and iodo groups.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Dye and Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and functional colorants.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Iodoaniline
CAS No.	1201149-19-0
Molecular Formula	C6H4BrFIN
Molecular Weight	315.91 g/mol
Synonyms	2-Fluoro-4-bromo-6-iodoaniline; 6-Iodo-2-fluoro-4-bromoaniline; 1-Amino-4-bromo-2-fluoro-6-iodobenzene; Benzenamine, 4-bromo-2-fluoro-6-iodo-; 4-Bromo-2-fluoro-6-iodobenzenamine; 4-Br-2-F-6-I-aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-6-Iodoaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.