Description

1-[4-(Trifluoromethoxy)Phenyl]Cyclopropan-1-Amine is a high-value, functionalized cyclopropylamine derivative featuring a trifluoromethoxy phenyl substituent. This compound is a critical pharmaceutical intermediate and organic building block prized for its unique structural motif, which can impart desirable metabolic stability and lipophilicity to target molecules. It is primarily utilized by research institutions and chemical manufacturers in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing advanced pesticides and herbicides, where the cyclopropane and trifluoromethoxy groups enhance bioactivity.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probe: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to pharmaceutical and biotechnology clients.

Basic Information

Product Name	1-[4-(Trifluoromethoxy)Phenyl]Cyclopropan-1-Amine
CAS No.	1200798-12-4
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]cyclopropanamine; 4-(1-Aminocyclopropyl)phenyl trifluoromethyl ether; 1-(4-Trifluoromethoxyphenyl)cyclopropylamine; α-(Trifluoromethoxy)cyclopropylbenzenamine; 1-Amino-1-[4-(trifluoromethoxy)phenyl]cyclopropane; 4-(Aminocyclopropyl)phenyl trifluoromethyl ether; (4-Trifluoromethoxyphenyl)cyclopropylamine
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethoxy)Phenyl]Cyclopropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.