Description

4-(Dimethylphosphoryl)-2-Fluoroaniline is a specialized organophosphorus building block featuring a unique combination of a phosphoryl group and a fluoro-substituted aniline. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific functional groups enable precise molecular modifications. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, pesticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in catalytic processes.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, or organic electronic materials due to its electron-withdrawing phosphoryl group.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring this specific fluorinated aniline derivative.

Basic Information

Product Name	4-(Dimethylphosphoryl)-2-Fluoroaniline
CAS No.	1197956-35-6
Molecular Formula	C8H11FNO2P
Molecular Weight	203.15 g/mol
Synonyms	2-Fluoro-4-(dimethylphosphoryl)aniline; 4-(Dimethylphosphinyl)-2-fluoroaniline; 2-Fluoro-4-(N,N-dimethylphosphoramidoyl)aniline; 4-(Dimethylphosphoryl)-2-fluoro-benzenamine; N,N-Dimethyl-P-(2-fluoro-4-aminophenyl)phosphinic amide; (2-Fluoro-4-aminophenyl)dimethylphosphine oxide
EINECS	Contact for details

Quality Control

Our 4-(Dimethylphosphoryl)-2-Fluoroaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.