Description

3'-Fluorobiphenyl-4-Ylaminehydrochloride is a high-purity, advanced pharmaceutical intermediate and fine chemical building block. Its value lies in its role as a key synthon for constructing complex molecules, particularly in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biphenyl scaffold for biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic amines used in the production of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, including polyimides and epoxy resins, to enhance thermal stability and optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the creation of novel chemical libraries for high-throughput screening.
• Dye & Pigment Industry: Utilized as a key intermediate in the synthesis of specialized fluorinated dyes and pigments that require high color fastness and stability.

Basic Information

Product Name	3'-Fluorobiphenyl-4-Ylaminehydrochloride
CAS No.	1197232-50-0
Molecular Formula	C12H11ClFN
Molecular Weight	223.67 g/mol
Synonyms	4-Amino-3'-fluorobiphenyl hydrochloride; 3'-Fluoro-[1,1'-biphenyl]-4-amine hydrochloride; 3-Fluorobiphenyl-4-amine HCl; 4-(3-Fluorophenyl)aniline hydrochloride; 3'-Fluoro-4-biphenylamine hydrochloride; 3-Fluoro-4-aminobiphenyl hydrochloride; (3'-Fluoro[1,1'-biphenyl]-4-yl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 3'-Fluorobiphenyl-4-Ylaminehydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.