Description

2-Chloro-7,8-Dihydro-6H-Quinazolin-5-One is a versatile and high-purity pharmaceutical intermediate with the CAS number 1196156-64-5. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with specific modes of action.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-Chloro-7,8-Dihydro-6H-Quinazolin-5-One
CAS No.	1196156-64-5
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydroquinazolin-5-one; 2-Chloro-7,8-dihydro-6H-quinazolin-5-one; 5(6H)-Quinazolinone, 2-chloro-7,8-dihydro-; 2-Chloro-5,6,7,8-tetrahydro-5-quinazolinone; 2-Chloro-5,8-dihydro-6H-quinazolin-5-one; 2-Chloro-7,8-dihydroquinazolin-5(6H)-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-7,8-Dihydro-6H-Quinazolin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.