Description

Ethyl 4-Methylpyrimidine-2-Carboxylate is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and antiviral applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyrimidine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.
• Academic and Industrial R&D: Essential for methodological development and exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	Ethyl 4-Methylpyrimidine-2-Carboxylate
CAS No.	1196156-62-3
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	2-Pyrimidinecarboxylic acid, 4-methyl-, ethyl ester; Ethyl 4-methyl-2-pyrimidinecarboxylate; 4-Methylpyrimidine-2-carboxylic acid ethyl ester; Ethyl 4-methylpyrimidine-2-carboxylate; 1196156-62-3; 4-Methyl-2-pyrimidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methylpyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production facilities adhere to ISO standards, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.