Description

5-Fluoropyrimidin-2-Yl)Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a fluorinated pyrimidine scaffold. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research, where its structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries engaged in developing next-generation small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, especially kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides that leverage the pyrimidine core for enhanced biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and cellular pathways.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	5-Fluoropyrimidin-2-Yl)Methanamine
CAS No.	1196155-99-3
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	(5-Fluoropyrimidin-2-yl)methanamine; 1-(5-Fluoropyrimidin-2-yl)methanamine; 2-(Aminomethyl)-5-fluoropyrimidine; 5-Fluoro-2-pyrimidinemethanamine; (5-Fluoro-2-pyrimidinyl)methylamine; 5-Fluoro-2-(aminomethyl)pyrimidine; 2-Aminomethyl-5-fluoropyrimidine
EINECS	Contact for details

Quality Control

Our 5-Fluoropyrimidin-2-Yl)Methanamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.