Description

4-Chloro-2-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical scaffold to accelerate drug discovery programs and synthesize advanced therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used as a core structure for developing new crop protection agents and herbicides.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study biological pathways.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	4-Chloro-2-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine
CAS No.	1196155-12-0
Molecular Formula	C9H10ClN3
Molecular Weight	195.65 g/mol
Synonyms	4-Chloro-2-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 2-Methyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 5,6,7,8-Tetrahydro-4-chloro-2-methylpyrido[3,4-d]pyrimidine; 4-Chloro-2-methyl-5,8-dihydropyrido[3,4-d]pyrimidine; CAS 1196155-12-0; Pyrido[3,4-d]pyrimidine, 4-chloro-2-methyl-5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.