Description

5-Ethynyl-2-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional pyrimidine derivative featuring both an ethynyl group and a trifluoromethyl substituent. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small-molecule drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic materials.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Chemical Biology Probe: Utilized in bio-conjugation and click chemistry applications for labeling and studying biological systems.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	5-Ethynyl-2-(Trifluoromethyl)Pyrimidine
CAS No.	1196153-54-4
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	2-(Trifluoromethyl)-5-ethynylpyrimidine; 5-Ethynyl-2-(trifluoromethyl)pyrimidine; 5-Ethynyl-2-trifluoromethylpyrimidine; 2-Trifluoromethyl-5-ethynylpyrimidine; Pyrimidine, 5-ethynyl-2-(trifluoromethyl)-; 1196153-54-4
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.