Description

2-[4-Methyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Ethan-1-Amine Hydrochloride is a high-purity, functionalized pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the pyrimidine scaffold and the trifluoromethyl group, which are pivotal for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials requiring fluorine-containing aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-[4-Methyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Ethan-1-Amine Hydrochloride
CAS No.	1196152-75-6
Molecular Formula	C8H9F3N3·HCl
Molecular Weight	243.63 g/mol (Free base: 207.17 g/mol)
Synonyms	2-(4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl)ethanamine hydrochloride; 2-(4-Methyl-6-(trifluoromethyl)-2-pyrimidinyl)ethylamine hydrochloride; 1-(4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl)ethanamine HCl; 2-Aminoethyl-4-methyl-6-(trifluoromethyl)pyrimidine hydrochloride; 4-Methyl-6-(trifluoromethyl)-2-pyrimidineethanamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-[4-Methyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Ethan-1-Amine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.