Description

2-Pyrimidyl Chloride (CAS NO 1195939-87-7) is a high-value, reactive heterocyclic building block essential for advanced chemical synthesis. Its core value lies in its pyrimidine scaffold and reactive chloride group, enabling precise molecular construction in complex organic frameworks. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require a pyrimidine core structure.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for tagging biomolecules or creating activity-based probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Pyrimidyl Chloride
CAS No.	1195939-87-7
Molecular Formula	C4H3ClN2
Molecular Weight	114.53 g/mol
Synonyms	2-Chloropyrimidine; Pyrimidine, 2-chloro-; 2-Pyrimidinyl chloride; Chloropyrimidine; 2-Chloro-1,3-diazine; 2-Pyrimidinecarbonyl chloride (related); 2-Pyrimidinecarboxylic acid chloride (related); 2-Pyrimidinoyl chloride (related)
EINECS	Contact for details

Quality Control

Our 2-Pyrimidyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.