Description

1,2,4-Triazolo[4,3-A]Pyrimidin-3-Amine is a high-value fused heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique triazolopyrimidine scaffold is essential for developing novel active pharmaceutical ingredients (APIs) and agrochemicals with targeted biological activity. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways in academic and industrial research.
• Material Science: Investigated as a building block for advanced organic electronic materials, such as ligands in coordination polymers or components in organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	1,2,4-Triazolo[4,3-A]Pyrimidin-3-Amine
CAS No.	1195625-75-2
Molecular Formula	C5H4N6
Molecular Weight	148.13 g/mol
Synonyms	3-Amino-1,2,4-triazolo[4,3-a]pyrimidine; 1,2,4-Triazolo[4,3-a]pyrimidin-3-amine; 1,2,4-Triazolo[4,3-a]pyrimidin-3-ylamine; [1,2,4]Triazolo[4,3-a]pyrimidin-3-amine; 1195625-75-2; 3-Amino-[1,2,4]triazolo[4,3-a]pyrimidine; 1,2,4-Triazolo[4,3-a]pyrimidine-3-amine
EINECS	Contact for details

Quality Control

Our 1,2,4-Triazolo[4,3-A]Pyrimidin-3-Amine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.