Description

Pyrimidine-5-Carboxamidine Hydrochloride is a high-purity chemical building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its functionalized pyrimidine core, which serves as a versatile precursor for the development of complex heterocyclic compounds. This material is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications in drug discovery, medicinal chemistry, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzymatic activity and biological pathways.
• Heterocyclic Compound Library Synthesis: A valuable reagent for combinatorial chemistry and the generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	Pyrimidine-5-Carboxamidine Hydrochloride
CAS No.	1195613-50-3
Molecular Formula	C5H7N4•HCl
Molecular Weight	158.60 g/mol
Synonyms	5-Carbamimidoylpyrimidine hydrochloride; 5-Pyrimidinecarboxamidine hydrochloride; 5-Cyanopyrimidine amidine hydrochloride; 5-Pyrimidinecarboximidamide hydrochloride; 5-Amidinopyrimidine HCl; Pyrimidine-5-carboxamidine HCl; 5-Carbamimidoylpyrimidin-1-ium chloride
EINECS	Contact for details

Quality Control

Our Pyrimidine-5-Carboxamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.