Description

3,4-Difluoro-5-Methoxybenzenamine is a high-purity aromatic amine derivative featuring a unique substitution pattern of fluorine and methoxy groups. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and advanced electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and nucleophilic aromatic substitution to construct complex heterocyclic and polyfunctional aromatic systems.
• Chemical Research: A valuable reagent for academic and industrial R&D in medicinal chemistry and process development for scale-up.

Basic Information

Product Name	3,4-Difluoro-5-Methoxybenzenamine
CAS No.	1195190-12-5
Molecular Formula	C7H7F2NO
Molecular Weight	159.13 g/mol
Synonyms	5-Methoxy-3,4-difluoroaniline; 3,4-Difluoro-5-methoxyaniline; 3,4-Difluoro-5-methoxy-phenylamine; 5-Amino-1,2-difluoro-3-methoxybenzene; Benzenamine, 3,4-difluoro-5-methoxy-; 3,4-Difluoro-5-methoxybenzenamine
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-5-Methoxybenzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-influenced synthesis and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.