Description

4-Methoxy-2-(1-Piperazinyl)Pyrimidine Dihydrochloride is a high-purity, non-hygroscopic salt form of a key heterocyclic building block. This compound is valued for its role as a versatile intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D laboratories and fine chemical manufacturers in the pharmaceutical, agrochemical, and life science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrimidine-piperazine scaffold.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes and tool compounds to study biological pathways.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploratory synthesis projects.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to introduce specific methoxy-pyrimidine motifs into target molecules.

Basic Information

Product Name	4-Methoxy-2-(1-Piperazinyl)Pyrimidine Dihydrochloride
CAS No.	1193389-74-0
Molecular Formula	C9H16Cl2N4O
Molecular Weight	267.16 g/mol
Synonyms	2-(Piperazin-1-yl)-4-methoxypyrimidine dihydrochloride; 4-Methoxy-2-piperazin-1-ylpyrimidine dihydrochloride; 4-Methoxy-2-(piperazin-1-yl)pyrimidine hydrochloride (1:2); 2-Piperazin-1-yl-4-methoxypyrimidine dihydrochloride; 4-Methoxy-2-(1-piperazinyl)pyrimidine, dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(1-Piperazinyl)Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for water content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.