Description

n-[4-Amino-3-(Trifluoromethyl)Phenyl]-5-Methyl-1,2-Oxazole-4-Carboxamide Hydrochloride is a high-purity, non-racemic organic compound featuring a trifluoromethylphenyl and oxazole core structure. This compound matters as a critical pharmaceutical intermediate or reference standard for research and development in medicinal chemistry. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced material sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.
• Agrochemical Development: Intermediate in the research and synthesis of novel pesticides or herbicides.
• Chemical Biology Probe: Utilized in biochemical assays to study specific protein interactions or enzymatic activity.
• Material Science: Potential precursor for advanced organic materials or ligands in catalytic systems.

Basic Information

Product Name	n-[4-Amino-3-(Trifluoromethyl)Phenyl]-5-Methyl-1,2-Oxazole-4-Carboxamide Hydrochloride
CAS No.	1193388-66-7
Molecular Formula	C12H11F3N4O2 • HCl
Molecular Weight	335.70 g/mol (Free base: 300.24 g/mol)
Synonyms	5-Methyl-N-[4-amino-3-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide hydrochloride; 4-Amino-3-(trifluoromethyl)phenyl 5-methylisoxazole-4-carboxamide HCl; 1193388-66-7; UNII-7Q3S2A4O4B; 7Q3S2A4O4B; SCHEMBL23306279; AKOS040759414; ZINC000006314757
EINECS	Contact for details

Quality Control

Our n-[4-Amino-3-(Trifluoromethyl)Phenyl]-5-Methyl-1,2-Oxazole-4-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with exacting research-grade standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.