Description

3-(4-(Aminomethyl)-1-(5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidine-4-Carboxamido)Phenyl Dimethylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is valued for its role as a key building block in the development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Oncology Research: Used in the development and optimization of novel anti-cancer compounds, leveraging its pyrrolopyrimidine core structure.
• Bioconjugation & Probe Development: Serves as a versatile scaffold for creating labeled probes or antibody-drug conjugates (ADCs) due to its reactive functional groups.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to enhance potency and selectivity.
• Process Chemistry & Scale-Up: Supplied for route scouting, process development, and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): A key material for organizations providing custom synthesis and development services.

Basic Information

Item	Details
Product Name	3-(4-(Aminomethyl)-1-(5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidine-4-Carboxamido)Phenyl Dimethylcarbamate
CAS No.	1192189-69-7
Molecular Formula	C24H29N7O3
Molecular Weight	463.54 g/mol
Synonyms	4-[[4-[[(Dimethylamino)carbonyl]oxy]phenyl]carbamoyl]-4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine; 1192189-69-7; UNII-9J8F1108IJ; 9J8F1108IJ; 3-(4-(Aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido)phenyl dimethylcarbamate; Pyrrolopyrimidine piperidine carboxamide derivative; (4-((4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamido)phenyl) dimethylcarbamate
EINECS	Contact for details

Quality Control

Our 3-(4-(Aminomethyl)-1-(5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidine-4-Carboxamido)Phenyl Dimethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing, adhering to ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. The compound is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.