Description

5-Fluoro-3-(Thien-2-Ylmethylene)-1,3-Dihydro-2H-Indol-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel small-molecule drugs, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its unique fluorinated indole scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a functional material in the synthesis of electron-transport or emissive layers for advanced display technologies.
• Academic & Contract Research: Employed in organic chemistry research for studying novel reaction pathways and synthesizing complex heterocyclic libraries.
• Dye & Pigment Industry: Acts as an intermediate for producing specialized fluorophores and high-performance pigments.

Basic Information

Product Name	5-Fluoro-3-(Thien-2-Ylmethylene)-1,3-Dihydro-2H-Indol-2-One
CAS No.	1191386-97-6
Molecular Formula	C₁₃H₈FNOS
Molecular Weight	245.27 g/mol
Synonyms	5-Fluoro-3-[(thiophen-2-yl)methylene]indolin-2-one; 2H-Indol-2-one, 5-fluoro-3-(2-thienylmethylene)-1,3-dihydro-; 5-Fluoro-3-(2-thienylmethylene)indolin-2-one; 5-Fluoro-3-(thiophen-2-ylmethylidene)-1,3-dihydro-2H-indol-2-one; 3-[(Thiophen-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(Thien-2-Ylmethylene)-1,3-Dihydro-2H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.