Description

4,6-Dichloro-2-(4-Chloro-3-Fluorophenyl)Pyrimidine is a high-purity halogenated pyrimidine derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its versatile reactivity, serving as a key building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• As a key synthetic intermediate in pharmaceutical research and development, particularly for kinase inhibitors and other small molecule drugs.
• In the synthesis of agrochemicals, including herbicides, fungicides, and insecticides, leveraging its halogenated pyrimidine core.
• For the preparation of functional materials and liquid crystals, where its structural rigidity and halogen atoms are beneficial.
• As a versatile building block in academic and industrial organic chemistry for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• In the development of chemical probes and diagnostic agents for biological research.

Basic Information

Product Name	4,6-Dichloro-2-(4-Chloro-3-Fluorophenyl)Pyrimidine
CAS No.	1190735-18-2
Molecular Formula	C10H4Cl3FN2
Molecular Weight	277.51 g/mol
Synonyms	2-(4-Chloro-3-fluorophenyl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(4-chloro-3-fluorophenyl)pyrimidine; 4,6-Dichloro-2-(4-chloro-3-fluorophenyl)-pyrimidine; 4,6-Dichloro-2-(4-chloro-3-fluoro-phenyl)pyrimidine; 2-(4-Chloro-3-fluorophenyl)-4,6-dichloro-pyrimidine; Pyrimidine, 4,6-dichloro-2-(4-chloro-3-fluorophenyl)-; 1190735-18-2
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(4-Chloro-3-Fluorophenyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.