Description

2-(N,n-Bisboc-Amino)Pyrimidine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid ester building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heteroaryl systems. This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules. The CAS number for this compound is 1190423-36-9.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing pyrimidine-containing drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with pyrimidine-based active cores.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Enables the synthesis of labeled compounds and molecular probes for biological target identification and validation.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry approaches.
• Custom Synthesis Services: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis.

Basic Information

Product Name	2-(N,n-Bisboc-Amino)Pyrimidine-5-Boronic Acid, Pinacol Ester
CAS No.	1190423-36-9
Molecular Formula	C₂₅H₃₈BN₃O₆
Molecular Weight	487.40 g/mol
Synonyms	2-(Bis(tert-butoxycarbonyl)amino)pyrimidine-5-boronic acid pinacol ester; 2-(Di-Boc-amino)pyrimidine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine, N,N-bis-Boc protected; 2-[(Bis(tert-butoxycarbonyl)amino]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-(N,N-Bis-Boc-amino)-5-(pinacolboronato)pyrimidine; 1190423-36-9; 2-(Bis-Boc-amino)-5-pyrimidineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(N,n-Bisboc-Amino)Pyrimidine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with full analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (H-NMR)	Conforms to structure
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.