Description

Methyl(S)-4-Oxo-4,6,7,8-Tetrahydropyrrolo[1,2-A]Pyrimidine-6-Carboxylate CAS NO 1190392-23-4 is a high-purity, chiral heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise stereochemistry, which is critical for developing bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring sophisticated pyrrolopyrimidine scaffolds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Asymmetric Synthesis: Serves as a building block for the construction of complex, enantiomerically pure molecules in academic and industrial laboratories.
• API Development: Employed in the synthesis of advanced intermediates for potential Active Pharmaceutical Ingredients (APIs) with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	Methyl(S)-4-Oxo-4,6,7,8-Tetrahydropyrrolo[1,2-A]Pyrimidine-6-Carboxylate
CAS No.	1190392-23-4
Molecular Formula	C10H10N2O3
Molecular Weight	206.20 g/mol
Synonyms	(S)-Methyl 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate; Methyl (6S)-4-oxo-6,7,8,9-tetrahydropyrimido[1,2-a]azepine-6-carboxylate; Methyl (S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate; 1190392-23-4; Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, methyl ester, (6S)-; (6S)-Methyl 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.