Description

n-[3-[[5-Cyclopropyl-2-[[3-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Propyl]Cyclobutanecarboxamide is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters for its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily needed by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in developing novel treatments for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel kinase inhibitor candidates for oncology research.
• Preclinical Drug Development: Used in the preparation of active pharmaceutical ingredients (APIs) for pharmacological and toxicological studies.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the efficient, scalable production of target molecules.
• Biochemical Assay Development: Utilized as a reference standard or probe compound in high-throughput screening and enzyme inhibition assays.
• Academic Research: Used in university and institutional labs for investigating cellular signaling pathways and disease mechanisms.

Basic Information

Product Name	n-[3-[[5-Cyclopropyl-2-[[3-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Propyl]Cyclobutanecarboxamide
CAS No.	1190378-57-4
Molecular Formula	C26H36N6O2
Molecular Weight	464.61 g/mol
Synonyms	N-[3-[[5-Cyclopropyl-2-[[3-(4-Morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide; 1190378-57-4; UNII-9J8K4V8H5M; 9J8K4V8H5M; Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-; CHEMBL3186471; BDBM50190071; AKOS025147064
EINECS	Contact for details

Quality Control

Our n-[3-[[5-Cyclopropyl-2-[[3-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Propyl]Cyclobutanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and MS), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.