Description

5-Fluoro-7-azaindole-3-carboxylic acid methyl ester is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in its fused azaindole scaffold, which serves as a privileged structure for designing potent and selective bioactive molecules. This compound is primarily needed by medicinal chemists and R&D teams in the pharmaceutical industry for the synthesis of novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, particularly for oncology and anti-inflammatory applications.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function.
• Material Science Precursor: Potential starting material for the synthesis of organic semiconductors or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services for clinical trial materials.

Basic Information

Product Name	5-Fluoro-7-azaindole-3-carboxylic acid methyl ester
CAS No.	1190314-69-2
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	Methyl 5-fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 5-Fluoro-7-aza-1H-indole-3-carboxylic acid methyl ester; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 5-F-7-AI-3-CME; 1190314-69-2; 5-Fluoro-7-azaindole-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 5-Fluoro-7-azaindole-3-carboxylic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.