Description

n-(2-{[(4-Hydroxy-6,7-Dimethoxyquinazolin-2-Yl)Methyl]Sulfanyl}Ethyl)-2-(1H-Indol-1-Yl)Acetamide is a sophisticated heterocyclic organic compound designed for advanced research and development. This molecule is significant for its unique structural features, combining quinazoline and indole moieties linked via a thioether and acetamide bridge, which are of high interest in medicinal chemistry. It is primarily sought by pharmaceutical researchers and fine chemical manufacturers for use as a key intermediate or reference standard in the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new drug candidates, particularly in oncology and CNS-related therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in biochemical assays and target validation studies to investigate specific enzyme or receptor interactions.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in API synthesis.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory synthetic chemistry and pharmacological studies.
• Custom Synthesis Starting Material: Acts as a specialized substrate for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	n-(2-{[(4-Hydroxy-6,7-Dimethoxyquinazolin-2-Yl)Methyl]Sulfanyl}Ethyl)-2-(1H-Indol-1-Yl)Acetamide
CAS No.	1190253-35-0
Molecular Formula	C24H24N4O4S
Molecular Weight	464.54 g/mol
Synonyms	N-[2-({[4-Hydroxy-6,7-dimethoxyquinazolin-2-yl]methyl}sulfanyl)ethyl]-2-(1H-indol-1-yl)acetamide; 2-(1H-Indol-1-yl)-N-[2-({[4-hydroxy-6,7-dimethoxyquinazolin-2-yl]methyl}sulfanyl)ethyl]acetamide; 1190253-35-0; Quinazoline-indole acetamide derivative; (4-Hydroxy-6,7-dimethoxyquinazolin-2-yl)methylsulfanyl-ethyl-indolylacetamide
EINECS	Contact for details

Quality Control

Our n-(2-{[(4-Hydroxy-6,7-Dimethoxyquinazolin-2-Yl)Methyl]Sulfanyl}Ethyl)-2-(1H-Indol-1-Yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.