Description

1-(2-Chloro-9H-Purin-6-Yl)-n-[(2E)-5-(Propan-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Piperidine-3-Carboxamide is a sophisticated heterocyclic organic compound designed for advanced research and development applications. This molecule is of significant interest due to its unique structural hybrid, combining purine and thiadiazole pharmacophores, which is pivotal for exploring novel biological activities. It serves as a critical building block and intermediate for medicinal chemists and researchers in the pharmaceutical and agrochemical sectors, particularly in the synthesis of targeted small molecule libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel purine-based therapeutics, including kinase inhibitors and antiviral agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening to identify new bioactive compounds.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition, receptor binding, and other cellular signaling pathways.
• Agrochemical Development: Investigated as an intermediate for creating new crop protection agents with potential fungicidal or herbicidal activity.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental organic synthesis and heterocyclic chemistry projects.
• Custom Synthesis & Scale-Up: Acts as a starting material for custom chemical synthesis services, supporting process development from milligram to kilogram scale.

Basic Information

Product Name	1-(2-Chloro-9H-Purin-6-Yl)-n-[(2E)-5-(Propan-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Piperidine-3-Carboxamide
CAS No.	1190247-92-7
Molecular Formula	C16H18ClN9OS
Molecular Weight	419.89 g/mol
Synonyms	1-(2-Chloro-9H-purin-6-yl)-N-[(2E)-5-(propan-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]piperidine-3-carboxamide; 1-(2-Chloro-9H-purin-6-yl)-N-[(2E)-5-isopropyl-1,3,4-thiadiazol-2(3H)-ylidene]piperidine-3-carboxamide; 1190247-92-7; 2-Chloro-6-[3-[[(2E)-5-(1-methylethyl)-1,3,4-thiadiazol-2(3H)-ylidene]carbamoyl]-1-piperidinyl]-9H-purine; Purine, 2-chloro-6-[3-[[(2E)-5-(1-methylethyl)-1,3,4-thiadiazol-2(3H)-ylidene]carbamoyl]-1-piperidinyl]-9H-
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-9H-Purin-6-Yl)-n-[(2E)-5-(Propan-2-Yl)-1,3,4-Thiadiazol-2(3H)-Ylidene]Piperidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable supply for your critical R&D and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.