Description

2-Bromo-4-Nitro-5-(Trifluoromethyl)Aniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromo, nitro, and trifluoromethyl substituents, makes it an invaluable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments, contributing to color fastness and stability.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostic applications.

Basic Information

Product Name	2-Bromo-4-Nitro-5-(Trifluoromethyl)Aniline
CAS No.	1190198-31-2
Molecular Formula	C7H4BrF3N2O2
Molecular Weight	285.02 g/mol
Synonyms	5-Amino-2-bromo-4-nitrobenzotrifluoride; 2-Bromo-4-nitro-5-(trifluoromethyl)benzenamine; 2-Bromo-5-amino-4-nitrobenzotrifluoride; 1-Amino-2-bromo-4-nitro-5-(trifluoromethyl)benzene; Benzenamine, 2-bromo-4-nitro-5-(trifluoromethyl)-; 2-Bromo-4-nitro-alpha,alpha,α-trifluoro-m-toluidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Nitro-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.