Description

1-(5-Bromopyrimidin-2-yl)ethanone is a high-purity brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its reactive bromine and ketone functional groups, enabling precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized heterocyclic compounds used in organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and affinity tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring bromopyrimidine scaffolds.
• Academic & R&D Laboratories: Used in methodological development and discovery chemistry for novel reaction pathways.

Basic Information

Product Name	1-(5-Bromopyrimidin-2-yl)ethanone
CAS No.	1189169-37-6
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	5-Bromo-2-acetylpyrimidine; 2-Acetyl-5-bromopyrimidine; Ethanone, 1-(5-bromo-2-pyrimidinyl)-; 1-(5-Bromo-2-pyrimidinyl)ethanone; 5-Bromo-2-pyrimidinyl methyl ketone; 1-(5-Bromopyrimidin-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyrimidin-2-yl)ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.