Description

3-[(6,7-Dimethoxy-4-Quinazolinyl)Oxy]Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its quinazoline-based molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel kinase inhibitors and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazoline-derived drug candidates, particularly kinase inhibitors.
• Oncology Research: Used in the R&D of targeted cancer therapies that interfere with specific cellular signaling pathways.
• Biochemical Tool Compound: Serves as a precursor for creating probes and inhibitors used in enzymatic and receptor binding studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex heterocyclic molecules in academic and industrial settings.
• API Development: Integral to the process development and scale-up of new chemical entities (NCEs) in pre-clinical and clinical stages.

Basic Information

Product Name	3-[(6,7-Dimethoxy-4-Quinazolinyl)Oxy]Aniline
CAS No.	1188908-37-3
Molecular Formula	C₁₆H₁₅N₃O₃
Molecular Weight	297.31 g/mol
Synonyms	3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]benzenamine; 3-(6,7-Dimethoxyquinazolin-4-yloxy)aniline; 4-(3-Aminophenoxy)-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-4-(3-aminophenoxy)quinazoline; Aniline, 3-[(6,7-dimethoxy-4-quinazolinyl)oxy]-; 1188908-37-3
EINECS	Contact for details

Quality Control

Our 3-[(6,7-Dimethoxy-4-Quinazolinyl)Oxy]Aniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.