Description

[2-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is a high-value, fluorinated cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a cyclopropyl ring and a trifluoromethylphenyl group, provides exceptional steric and electronic properties for modulating the biological activity and physicochemical profile of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create novel active ingredients with improved potency, selectivity, and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	[2-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol
CAS No.	1188541-93-6
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	(2-(3-(Trifluoromethyl)phenyl)cyclopropyl)methanol; α-(3-Trifluoromethylphenyl)cyclopropanemethanol; [2-(3-Trifluoromethylphenyl)cyclopropyl]methanol; (2-(3-(Trifluoromethyl)phenyl)cyclopropane-1-yl)methanol; 1-((3-(Trifluoromethyl)phenyl)cyclopropyl)methanol; CPD 1188541-93-6
EINECS	Contact for details

Quality Control

Our [2-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.