Description

4,6-Dichloro-5-Nitro-2-(Pyridin-2-Yl)Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive dichloro and nitro substituents, which allow for selective, sequential functionalization to create complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and scale-up of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology: Employed as a probe or linker molecule in the design of chemical tools for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in heterocyclic and nucleophilic aromatic substitution chemistry.

Basic Information

Product Name	4,6-Dichloro-5-Nitro-2-(Pyridin-2-Yl)Pyrimidine
CAS No.	1188037-64-0
Molecular Formula	C9H4Cl2N4O2
Molecular Weight	271.06 g/mol
Synonyms	2-(2-Pyridinyl)-4,6-dichloro-5-nitropyrimidine; 4,6-Dichloro-5-nitro-2-(2-pyridinyl)pyrimidine; 5-Nitro-4,6-dichloro-2-(pyridin-2-yl)pyrimidine; 4,6-Dichloro-5-nitro-2-pyridin-2-ylpyrimidine; Pyrimidine, 4,6-dichloro-5-nitro-2-(2-pyridinyl)-; DNPP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-Nitro-2-(Pyridin-2-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.