Description

(R)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine is a high-value chiral amine building block characterized by its trifluoromethyl and fluorophenyl substituents. This compound is essential for pharmaceutical research and development, particularly in the synthesis of active pharmaceutical ingredients (APIs) where its unique fluorine pattern can enhance metabolic stability and bioavailability. It is primarily sought by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel, patentable molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of fluorinated drug candidates, including potential CNS agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in developing advanced, fluorinated pesticides and herbicides where the fluorine atoms contribute to improved activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the creation of specialty monomers and fluorinated polymers with specific optical or electronic properties.
• Diagnostic Reagent Precursor: Utilized in the synthesis of fluorinated probes and tags for bioimaging and analytical applications.

Basic Information

Product Name	(R)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine
CAS No.	1187928-53-5
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	(R)-1-(3-Fluorophenyl)-2,2,2-trifluoroethanamine; (R)-α-(Trifluoromethyl)-3-fluorobenzeneethanamine; (R)-3-Fluoro-α-(trifluoromethyl)benzylamine; (R)-2,2,2-Trifluoro-1-(3-fluorophenyl)ethylamine; (R)-1-(3-Fluorophenyl)-2,2,2-trifluoroethylamine; (R)-TFMPEA; (R)-3-Fluoro-α-trifluoromethylbenzylamine
EINECS	Contact for details

Quality Control

Our (R)-2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (typically >99%), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.