Description

(R)-2,2,2-Trifluoro-1-(4-(Trifluoromethyl)Phenyl)Ethanamine is a high-value, chiral fluorinated amine building block essential for modern synthetic chemistry. Its core value lies in its unique trifluoromethylated aromatic structure, which imparts significant metabolic stability and lipophilicity to target molecules, making it a critical intermediate in advanced pharmaceutical development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Key chiral intermediate in the synthesis of pharmaceutical candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Building block for the development of advanced agrochemicals, where the fluorine atoms enhance biological activity and environmental stability.
• Precursor for ligands and catalysts used in asymmetric synthesis, leveraging its chiral center to induce stereoselectivity.
• Research chemical for studying structure-activity relationships (SAR) in medicinal chemistry due to its distinct electronic and steric properties.
• Intermediate in the production of specialty materials, such as liquid crystals or fluorinated polymers, where its aromatic and fluorinated nature is beneficial.

Basic Information

Product Name	(R)-2,2,2-Trifluoro-1-(4-(Trifluoromethyl)Phenyl)Ethanamine
CAS No.	1187928-03-5
Molecular Formula	C9H7F6N
Molecular Weight	243.15 g/mol
Synonyms	(R)-α,α,α-Trifluoro-4-(trifluoromethyl)benzylamine; (R)-1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethanamine; (R)-2,2,2-Trifluoro-1-[4-(trifluoromethyl)phenyl]ethylamine; (R)-4-(Trifluoromethyl)α-(trifluoromethyl)benzylamine; (R)-1-(4-Trifluoromethylphenyl)-2,2,2-trifluoroethylamine; (R)-TTPA; (R)-TTPE
EINECS	Contact for details

Quality Control

Our (R)-2,2,2-Trifluoro-1-(4-(Trifluoromethyl)Phenyl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.