Description

4-Fluoro-2-Trifluoromethyl-Benzamidine Hydrochloride is a high-purity, fluorinated benzamidine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the amidine functional group into complex molecular architectures, enabling the development of novel active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other enzyme-targeting drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the stability imparted by the fluorine substituents.
• Chemical Biology Research: Serves as a versatile precursor for designing molecular probes and inhibitors to study enzyme mechanisms and protein function.
• Material Science: Potential building block for specialty polymers and advanced materials requiring specific chemical functionality and stability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Fluoro-2-Trifluoromethyl-Benzamidine Hydrochloride
CAS No.	1187927-62-3
Molecular Formula	C8H7ClF4N2
Molecular Weight	242.60 g/mol
Synonyms	4-Fluoro-2-(trifluoromethyl)benzamidine hydrochloride; 2-Trifluoromethyl-4-fluorobenzamidine HCl; Benzenecarboximidamide, 4-fluoro-2-(trifluoromethyl)-, hydrochloride (1:1); 4-Fluoro-α,α,α-trifluoro-o-toluamidine hydrochloride; 4-Fluoro-2-trifluoromethylbenzenecarboximidamide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Trifluoromethyl-Benzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.