Description

Ethyl 2-(5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Yl)-Acetate Hcl is a high-purity pharmaceutical intermediate and building block of significant interest in medicinal chemistry research. Its core value lies in its role as a versatile precursor for synthesizing novel drug candidates, particularly kinase inhibitors targeting various therapeutic areas. This compound is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors focused on oncology, inflammation, and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced kinase inhibitor drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Oncology Drug Development: Serves as a precursor for compounds targeting specific protein kinases involved in cancer cell proliferation.
• Biochemical Assay Development: Employed as a reference standard or tool compound in high-throughput screening (HTS) and enzymatic assays.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for complex, multi-step organic syntheses.
• Academic Research: Used in university and institutional labs for exploratory research in heterocyclic and pharmaceutical chemistry.

Basic Information

Item	Details
Product Name	Ethyl 2-(5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Yl)-Acetate Hydrochloride
CAS No.	1187830-78-9
Molecular Formula	C13H18ClN3O2
Molecular Weight	283.75 g/mol
Synonyms	4-Pyrido[4,3-d]pyrimidineacetic acid, 5,6,7,8-tetrahydro-, ethyl ester, hydrochloride; Ethyl (5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)acetate hydrochloride; Ethyl 2-(5,6,7,8-tetrahydro-4-pyrido[4,3-d]pyrimidinyl)acetate HCl; 1187830-78-9; UNII-9F6K1F8V39; SCHEMBL23306227; 9F6K1F8V39
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-4-Yl)-Acetate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.