Description

5,6,7,8-Tetrahydro-4-Methylpyrido[3,4-D]Pyrimidine Hcl is a high-purity pharmaceutical intermediate and building block with the CAS number 1187830-72-3. This compound is valued for its role as a critical synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality raw materials for complex synthesis.

Application

• Key intermediate in the synthesis of kinase inhibitor drug candidates for oncology and inflammatory diseases.
• Building block for research into central nervous system (CNS) targeted therapeutics.
• Precursor in the development of pharmaceutical reference standards and analytical markers.
• Used in process chemistry and scale-up for Active Pharmaceutical Ingredient (API) manufacturing.
• Valuable reagent in academic and industrial R&D for heterocyclic and medicinal chemistry.
• Starting material for custom synthesis and the production of specialty fine chemicals.

Basic Information

Product Name	5,6,7,8-Tetrahydro-4-Methylpyrido[3,4-D]Pyrimidine Hydrochloride
CAS No.	1187830-72-3
Molecular Formula	C9H14ClN3
Molecular Weight	199.68 g/mol
Synonyms	4-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 5,6,7,8-Tetrahydro-4-methylpyrido[3,4-d]pyrimidine HCl; 4-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl; Tetrahydro-4-methylpyrido[3,4-d]pyrimidine hydrochloride; 1187830-72-3; Pyrido[3,4-d]pyrimidine, 5,6,7,8-tetrahydro-4-methyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-4-Methylpyrido[3,4-D]Pyrimidine Hcl is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.