Description

7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidinehydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187830-71-2. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing complex, biologically active molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the construction of potent and selective kinase inhibitors, a major class of targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to improve drug efficacy and safety profiles.
• Preclinical Drug Development: Employed in the synthesis of candidate compounds for pharmacological evaluation and toxicology studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery and development projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidinehydrochloride
CAS No.	1187830-71-2
Molecular Formula	C₁₇H₁₇ClN₄·HCl
Molecular Weight	349.26 g/mol
Synonyms	4-Chloro-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl; 1187830-71-2; 4-Chloro-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidine hydrochloride; Pyrido[3,4-d]pyrimidine, 4-chloro-5,6,7,8-tetrahydro-7-(phenylmethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Every batch of 7-Benzyl-4-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidinehydrochloride is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.