Description

Ethyl 2-(5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl)-Acetate Hcl is a high-purity pharmaceutical intermediate and building block of significant interest in modern medicinal chemistry. This compound matters for its role as a key precursor in the synthesis of complex heterocyclic molecules, enabling the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology, CNS disorders, and kinase inhibitor development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel therapeutic candidates.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex fused pyrimidine and pyridine ring systems.
• Biochemical Research: Employed in the development of chemical probes for studying enzyme function and cellular signaling pathways.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery programs.

Basic Information

Product Name	Ethyl 2-(5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl)-Acetate Hcl
CAS No.	1187830-52-9
Molecular Formula	C13H18ClN3O2
Molecular Weight	283.75 g/mol
Synonyms	Ethyl 2-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)acetate hydrochloride; 4-Pyrido[3,4-d]pyrimidineacetic acid, 5,6,7,8-tetrahydro-, ethyl ester, hydrochloride; Ethyl (5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)acetate HCl; 1187830-52-9; Tetrahydropyridopyrimidine acetate ethyl ester HCl
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4-Yl)-Acetate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.