Description

4-(1-(1-Ethoxyethyl)-1H-Pyrazol-4-Yl)-7-((2-(Trimethylsilyl)Ethoxy)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical synthesis and research. This compound is critical for medicinal chemists developing targeted therapies, particularly in oncology and antiviral drug discovery. It is primarily utilized by R&D laboratories and API manufacturers requiring precise, reliable building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Oncology Drug Discovery: Used in research and development of potential anti-cancer agents, leveraging the pyrrolo[2,3-d]pyrimidine core structure.
• Antiviral Agent Synthesis: Serves as a precursor in the development of compounds with potential antiviral activity.
• Chemical Biology Research: Employed as a probe or tool compound for studying specific biological pathways and protein interactions.
• Process Chemistry Development: Used in scaling up synthetic routes for new chemical entities (NCEs) during process optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific advanced intermediates.

Basic Information

Product Name	4-(1-(1-Ethoxyethyl)-1H-Pyrazol-4-Yl)-7-((2-(Trimethylsilyl)Ethoxy)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1187595-88-5
Molecular Formula	C19H30N4O2Si
Molecular Weight	374.56 g/mol
Synonyms	7H-Pyrrolo[2,3-d]pyrimidine, 4-[1-(1-ethoxyethyl)-1H-pyrazol-4-yl]-7-[[2-(trimethylsilyl)ethoxy]methyl]-; 4-(1-(1-Ethoxyethyl)-1H-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine; 1187595-88-5; SEM-Protected Pyrrolopyrimidine Intermediate; Kinase Inhibitor Intermediate; Pyrazolyl Pyrrolopyrimidine Derivative
EINECS	Contact for details

Quality Control

Our 4-(1-(1-Ethoxyethyl)-1H-Pyrazol-4-Yl)-7-((2-(Trimethylsilyl)Ethoxy)Methyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate to ensure long-term stability. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.