Description

4-Bromo-3-n-Methylaminobenzotrifluoride is a high-value fluorinated aromatic building block characterized by its bromine and methylamino functional groups. This compound is essential for facilitating complex molecular transformations in advanced chemical synthesis, offering a unique combination of reactivity and structural diversity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring trifluoromethyl and halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the benzotrifluoride core enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its fluorine content and aromatic structure.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for constructing complex biaryl systems.
• Chemical Derivatization: The methylamino group provides a handle for further functionalization through acylation, sulfonylation, or reductive amination to create diverse chemical libraries.

Basic Information

Product Name	4-Bromo-3-n-Methylaminobenzotrifluoride
CAS No.	1187386-33-9
Molecular Formula	C8H7BrF3N
Molecular Weight	254.05 g/mol
Synonyms	4-Bromo-3-(methylamino)benzotrifluoride; 3-Methylamino-4-bromobenzotrifluoride; 2-Bromo-6-(trifluoromethyl)-N-methylaniline; 4-Bromo-3-(N-methylamino)benzotrifluoride; 1-Bromo-2-methylamino-5-(trifluoromethyl)benzene; 4-Bromo-3-methylaminobenzotrifluoride; 4-Bromo-3-(methylamino)-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-n-Methylaminobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.