Description

2-Chloro-4-(Trifluoromethoxy)Aniline, Hcl is a high-purity, halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethoxy substituents, makes it a versatile intermediate for creating compounds with tailored electronic and steric properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its electron-withdrawing characteristics.
• Dye & Pigment Manufacturing: Employed in the production of specialized dyes and pigments, where the chlorine and fluorine atoms contribute to color fastness and unique spectral properties.
• Polymer Science: Acts as a monomer or modifier in the synthesis of high-performance polymers, such as polyimides and polyamides, for applications requiring thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethoxy)Aniline, Hcl
CAS No.	1187386-31-7
Molecular Formula	C7H6ClF3NO•HCl
Molecular Weight	262.49 g/mol (Free base: 225.58 g/mol)
Synonyms	2-Chloro-4-(trifluoromethoxy)benzenamine hydrochloride; 1-Amino-2-chloro-4-(trifluoromethoxy)benzene hydrochloride; 2-Chloro-4-(trifluoromethoxy)phenylamine HCl; 2-Chloro-α,α,α-trifluoro-p-anisidine hydrochloride; 4-Amino-3-chloro-1-(trifluoromethoxy)benzene hydrochloride; Benzenamine, 2-chloro-4-(trifluoromethoxy)-, hydrochloride; 2-Chloro-4-trifluoromethoxyaniline hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethoxy)Aniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.