Description

4-(2,6-Difluorobenzoyl)-2-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its difluorobenzoyl and methylpyridine functional groups. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its fluorinated aromatic structure for enhanced bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in medicinal and synthetic chemistry.
• Material Science Research: Investigated for potential use in the synthesis of specialty polymers and organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	4-(2,6-Difluorobenzoyl)-2-Methylpyridine
CAS No.	1187167-46-9
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	2-Methyl-4-(2,6-difluorobenzoyl)pyridine; 4-(2,6-Difluorobenzoyl)-2-picoline; 2-Picoline, 4-(2,6-difluorobenzoyl)-; 2,6-Difluoro-4-(2-methylpyridin-4-yl)phenyl methanone; (2,6-Difluorophenyl)(2-methylpyridin-4-yl)methanone
EINECS	Contact for details

Quality Control

Every batch of 4-(2,6-Difluorobenzoyl)-2-Methylpyridine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity requirements typical for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.