Description

4-Methoxy-2-(Methylsulfanyl)-6-(Trifluoromethyl)-5-Pyrimidinecarboxylic Acid is a high-purity, multi-functional pyrimidine derivative, serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in the unique trifluoromethyl and methoxy substituents, which are key for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of specialty chemicals and functional materials requiring specific pyrimidine-based architectures.

Basic Information

Product Name	4-Methoxy-2-(Methylsulfanyl)-6-(Trifluoromethyl)-5-Pyrimidinecarboxylic Acid
CAS No.	1186404-89-6
Molecular Formula	C8H7F3N2O3S
Molecular Weight	268.21 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 4-methoxy-2-(methylthio)-6-(trifluoromethyl)-; 4-Methoxy-2-methylsulfanyl-6-trifluoromethylpyrimidine-5-carboxylic acid; 2-(Methylthio)-4-methoxy-6-(trifluoromethyl)pyrimidine-5-carboxylic acid; 6-(Trifluoromethyl)-4-methoxy-2-(methylthio)pyrimidine-5-carboxylic acid; CAS 1186404-89-6
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Methylsulfanyl)-6-(Trifluoromethyl)-5-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.