Description

3-Amino-2-Fluorophenol is a versatile fluorinated aromatic building block featuring both amino and phenolic functional groups. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial applications. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Dye and Pigment Manufacturing: Employed in the production of high-performance dyes, pigments, and imaging agents due to its phenolic and aniline characteristics.
• Polymer Modification: Acts as a monomer or additive for engineering polymers to impart specific properties like thermal stability or chemical resistance.
• Research and Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Amino-2-Fluorophenol
CAS No.	1186326-66-8
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-Fluoro-3-aminophenol; 3-Amino-2-fluorophenol; 2-Fluoro-3-hydroxyaniline; 3-Hydroxy-2-fluoroaniline; 1-Amino-2-fluoro-3-hydroxybenzene; o-Fluoro-m-aminophenol; Phenol, 3-amino-2-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.