Description

(2S)-4-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Butanoic Acid is a high-purity, non-natural amino acid derivative featuring orthogonal protecting groups, making it a critical building block for advanced peptide synthesis. This compound is engineered to provide exceptional control and efficiency in solid-phase peptide synthesis (SPPS), particularly in the construction of complex or therapeutic peptides. It is an essential raw material for pharmaceutical R&D, biotechnology, and fine chemical synthesis, enabling the production of novel drug candidates and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid derivative for the sequential assembly of peptide chains on resin.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of peptide-based therapeutics, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: Used to introduce specific functional handles or linkers into peptides for labeling, drug delivery systems, or antibody-drug conjugate (ADC) development.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds and lead optimization.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and interactions in biochemistry and molecular biology.
• Custom Peptide Service: Supplied to CROs and CDMOs specializing in the custom synthesis of peptides for clinical and commercial applications.

Basic Information

Product Name	(2S)-4-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Butanoic Acid
CAS No.	1185841-92-2
Molecular Formula	C27H25NO5
Molecular Weight	443.49 g/mol
Synonyms	Fmoc-Ser(Bzl)-OH; Fmoc-O-benzyl-L-serine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-benzyl-L-serine; Fmoc-L-Ser(Bzl)-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(phenylmethoxy)propanoic Acid; Nα-Fmoc-O-benzyl-L-serine; Fmoc-Ser(OBzl)-OH; Fmoc-O-Benzylserine
EINECS	Contact for details

Quality Control

Our (2S)-4-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.