Description

Fmoc-L-Arg(Me)2(Pbf)-Oh CAS NO 1185841-84-2 is a protected derivative of L-arginine, specifically engineered for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers who require high-purity, side-chain protected amino acids to ensure successful and efficient peptide chain assembly. It is an essential building block for pharmaceutical R&D, particularly in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated and manual synthesis of complex peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics targeting various diseases.
• Bioconjugation: Serves as a modified arginine residue for creating labeled peptides or peptide-protein conjugates for diagnostic and research purposes.
• Combinatorial Chemistry: A vital component in libraries for high-throughput screening to identify bioactive peptide leads.
• Academic & Institutional Research: Employed in biochemistry and molecular biology laboratories for studying protein-protein interactions and enzyme mechanisms.
• Custom Peptide Service Providers: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Fmoc-L-Arg(Me)2(Pbf)-Oh
CAS No.	1185841-84-2
Molecular Formula	C₃₃H₄₇N₅O₇S
Molecular Weight	657.83 g/mol
Synonyms	Fmoc-Nω,Nω'-dimethyl-Nω''-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine; Fmoc-Arg(Me,Pbf)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω,Nω'-dimethyl-Nω''-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine; Fmoc-L-arginine(Nω,Nω'-dimethyl, Nω''-Pbf)-OH; Fmoc-Arg(Me)2(Pbf)-OH; Fmoc-NG,NG'-dimethyl-NG''-Pbf-L-arginine
EINECS	Contact for details

Quality Control

Our Fmoc-L-Arg(Me)2(Pbf)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC), chiral purity, and moisture content. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.