Description

4-Methoxy-6-Piperazin-1-Yl-Pyrimidine Hydrochloride is a high-purity pyrimidine derivative, a crucial building block in modern organic synthesis. This compound, with a molecular formula of C9H15ClN4O and a molecular weight of 230.69, is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical chemistry, particularly for medicinal chemists and process development scientists seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• Process Chemistry & Scale-up: Serves as a key starting material or intermediate in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Potential application as an intermediate in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying biological pathways and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific heterocyclic scaffolds.

Basic Information

Item	Details
Product Name	4-Methoxy-6-Piperazin-1-Yl-Pyrimidine Hydrochloride
CAS No.	1185313-57-8
Molecular Formula	C9H15ClN4O
Molecular Weight	230.69 g/mol
Synonyms	6-(Piperazin-1-yl)-4-methoxypyrimidine hydrochloride; 4-Methoxy-6-(piperazin-1-yl)pyrimidine HCl; 4-Methoxy-6-piperazin-1-ylpyrimidine hydrochloride; 6-Piperazin-1-yl-4-methoxypyrimidine hydrochloride; 1-(4-Methoxy-6-pyrimidinyl)piperazine hydrochloride; 4-Methoxy-6-(1-piperazinyl)pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-6-Piperazin-1-Yl-Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the specified purity of 98+% and consistent quality suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.