Description

4-Chloro-6-(Piperidin-3-Yloxy)-Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C9H13Cl2N3O and a molecular weight of 250.12. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule therapeutics, particularly kinase inhibitors. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and development programs targeting oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other bioactive molecules.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific biological pathways and protein functions.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological research.

Basic Information

Product Name	4-Chloro-6-(Piperidin-3-Yloxy)-Pyrimidine Hydrochloride
CAS No.	1185311-81-2
Molecular Formula	C9H13Cl2N3O
Molecular Weight	250.12 g/mol
Synonyms	4-Chloro-6-(3-piperidinyloxy)pyrimidine hydrochloride; 4-Chloro-6-(piperidin-3-yloxy)pyrimidine HCl; 6-(Piperidin-3-yloxy)-4-chloropyrimidine hydrochloride; 1185311-81-2; 4-Chloro-6-(3-piperidyloxy)pyrimidine hydrochloride; Pyrimidine, 4-chloro-6-(3-piperidinyloxy)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Piperidin-3-Yloxy)-Pyrimidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.